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Please use this identifier to cite or link to this item: http://ri.uaemex.mx/handle20.500.11799/71035
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dc.contributor.authorLucía García Iniestaen_EU
dc.contributor.authorBEATRIZ ELINA MARTINEZ CARRILLOen_EU
dc.contributor.authorROXANA VALDES RAMOSen_EU
dc.contributor.authorROSA ADRIANA JARILLO LUNAen_EU
dc.contributor.authorJORGE ALBERTO ESCOTO HERRERAen_EU
dc.contributor.authorALDO ARTURO RESENDIZ ALBORen_EU
dc.creatorLucía García Iniesta-
dc.creatorBEATRIZ ELINA MARTINEZ CARRILLO-
dc.creatorROXANA VALDES RAMOS-
dc.creatorROSA ADRIANA JARILLO LUNA-
dc.creatorJORGE ALBERTO ESCOTO HERRERA-
dc.creatorALDO ARTURO RESENDIZ ALBOR-
dc.date2017-10-16-
dc.date.accessioned2019-01-30T07:01:01Z-
dc.date.available2019-01-30T07:01:01Z-
dc.identifierhttp://hdl.handle.net/20.500.11799/71035-
dc.identifier.urihttp://ri.uaemex.mx/handle20.500.11799/71035-
dc.descriptionArtículo derivado de un proyecto de investigación para la identificación del efecto del consumo de edulcorantes sobre el sistema inmunitario.-
dc.descriptionIntroduction: Modern lifestyles have changed eating habits, encouraged physical inactivity, and increased stress in daily life. These living conditions cause elevated concentrations of carbonylated proteins like biomarker of oxidative stress. The expression of this proteins represent irreversible damage to structural intracellular proteins in cells and extracellular matrix. It is not clear whether a rise in the concentration of these proteins is the origin or consequence of diseases. Objective: To determine in a healthy young mice model the possible correlation between prolonged sweetener consumption and the presence of chronic physiological stress, evidenced by the production of carbonylated proteins in peripheral blood lymphocytes. Methods: Sixty-four 21-day-old CD1 male mice were divided into two groups, stressed (with immobilization) and unstressed. Each group was divided into four subgroups: Control or experimental with a 6-week administration of sucrose, sucralose or stevia. Body mass index, food intake, number and concentration of carbonylated proteins, levels of glucose and peripheral lymphocytes in blood were evaluated. Data were analyzed with ANOVA. Results: Compared to the unstressed control, the glucose concentration was elevated in all stressed subgroups (F = 13.41, p < 0.01), with greater weight found in the stressed sucralose supplemented subgroup (F = 77.58, p < 0.001). The blood level of peripheral lymphocytes was above the control in all subgroups (F = 19.97, p < 0.01), except the decrease observed in unstressed sucrose supplemented subgroup. Carbonylated protein concentration in peripheral blood lymphocytes was high in all subgroups (versus the control) except in unstressed animals suppelemented with stevia (F = 51.16, p <0.01). Conclusions: Stress plus sucralose increased number of lymphocytes and carbonylated proteins concentration. The physiological stress with or without sweetener consumption generated increase in carbonylated proteins concentration. Stevia did not modify lymphocytes and carbonylated proteins.-
dc.languageeng-
dc.publisherScience Domain International-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttp://creativecommons.org/licenses/by/4.0-
dc.source2347-5641-
dc.subjectproteínas carboniladas-
dc.subjectestrés-
dc.subjectlinfocitos-
dc.subjectEdulcorantes-
dc.subjectinfo:eu-repo/classification/cti/2-
dc.titleRelationship between prolonged sweetener consumption and chronic stress in the production of carbonylated proteins in blood lymphocytes-
dc.typearticle-
dc.audiencestudents-
dc.audienceresearchers-
item.fulltextNo Fulltext-
item.grantfulltextnone-
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