Phenytoin (PHE) is an antiepileptic drug that has been widely used in clinical practice for about 80 years. It is mainly used in the treatment of tonic-clonic and partial seizures. The widespread consumption of this drug ...

Fluoxetine (FLX) is a psychoactive drug that acts as an antidepressant. FLX is one of the world's best-selling pre- scription antidepressants. FLX is widely used for the treatment of various psychiatric disorders. For these ...

Fluoxetine (FLX) exerts its therapeutic effect by inhibiting the presynaptic reuptake of the neurotransmitter serotonin. Nonetheless, at high concentrations of this drug, adverse effects occur in the brain of exposed or- ...

Several studies have reported the presence of phenytoin (PHE) in wastewater treatment plant effluents, hospital efflu- ents, surface water, and even drinking water. However, published studies on the toxic effects of PHE ...