1. DSpace-CRIS UAEMEX
  2. Interoperabilidad Repositorio Nacional
  3. Producción
Please use this identifier to cite or link to this item: http://ri.uaemex.mx/handle20.500.11799/39328
DC FieldValueLanguage
dc.creatorRICARDO ABRAHAM DE LA CRUZ CORDERO-
dc.creatorVICTORIA LABASTIDA GALVAN-
dc.creatorMARIO FERNANDEZ ZERTUCHE-
dc.creatorJOSE MARIO ORDOÑEZ PALACIOS-
dc.date2005-
dc.date.accessioned2022-04-21T05:12:00Z-
dc.date.available2022-04-21T05:12:00Z-
dc.identifierhttp://hdl.handle.net/20.500.11799/39328-
dc.identifier.urihttp://ri.uaemex.mx/handle20.500.11799/39328-
dc.descriptionReduction of (3S)-N,N-dibenzylamino-2-ketophosphonates 9a-d derived from L-amino acids was carried out with catecholborane at -20 oC to afford the (3S)-N,N-dibenzylamino-(2R)-hydroxy-phosphonates syn-10a-d, whereas the reduction of (3S)-N-benzylamino-2- ketophosphonates 13a-d with Zn(BH4)2 at -78 oC yield (3S)-N-benzylamino-( 2S)-hydroxyphosphonates anti-14a-d. The reduction in both cases was in good chemical yields and with high diastereoselectivity. The hydrolysis and hydrogenolysis of 10a-d and 14a-d afford the (3S)-amino-(2R)-hydroxyphosphonic acids 6 and (3S)-amino-(2S)- hydroxyphosphonic acids 7, respectively, which are analogues of phosphostatine.-
dc.formatapplication/application/pdf-
dc.languageeng-
dc.publisherSociedad Química de México-
dc.relationhttp://www.redalyc.org/revista.oa?id=475-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0-
dc.sourceJournal of the Mexican Chemical Society (México) Num.4 Vol.49-
dc.subjectQuímica-
dc.subjectPhosphostatine-
dc.subjectaminophosphonic acids-
dc.subjectβ-ketophosphonates,-
dc.subjectdiastereoselective reduction-
dc.subjectinfo:eu-repo/classification/cti/2-
dc.titlePreparation of Phosphostatine Analogues From L-amino acids-
dc.typearticle-
dc.audiencestudents-
dc.audienceresearchers-
item.grantfulltextnone-
item.fulltextNo Fulltext-
Appears in Collections:Producción
Show simple item record

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.