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Please use this identifier to cite or link to this item: http://ri.uaemex.mx/handle20.500.11799/67817
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dc.contributor.authorMaría Guadalupe González Pedrozaen_EU
dc.contributor.authorVíctor Sánchez Mendietaen_EU
dc.contributor.authorJORGE A. MORALES VALENCIAen_EU
dc.contributor.authorGUSTAVO LOPEZ TELLEZen_EU
dc.contributor.authorLILIANA ARGUETA FIGUEROAen_EU
dc.contributor.authorOSCAR GONZALEZ PEREZen_EU
dc.contributor.authorRAUL ALBERTO MORALES LUCKIEen_EU
dc.creatorMaría Guadalupe González Pedroza-
dc.creatorVíctor Sánchez Mendieta-
dc.creatorJORGE A. MORALES VALENCIA-
dc.creatorGUSTAVO LOPEZ TELLEZ-
dc.creatorLILIANA ARGUETA FIGUEROA-
dc.creatorOSCAR GONZALEZ PEREZ-
dc.creatorRAUL ALBERTO MORALES LUCKIE-
dc.date2017-01-05-
dc.date.accessioned2019-03-12T23:44:04Z-
dc.date.available2019-03-12T23:44:04Z-
dc.identifierhttp://hdl.handle.net/20.500.11799/67817-
dc.identifier.urihttp://ri.uaemex.mx/handle20.500.11799/67817-
dc.descriptionNowadays, biomedical applications of gold nanoparticles coupled with Epidermal Growth Factor have attracted huge attention because of its theranostic activity, which could be useful for diagnosis and treatment of neurodegenerative diseases. Therefore, there is a great interest to know the nature of the intermolecular interactions between the gold nanoparticles and epidermal growth factor (EGF). A two-step synthesis was performed. In the first step, gold nanoparticles were synthesized by chemical reduction of tetrachloroauric acid using sodium citrate as reducing and capping agent. Secondly, gold nanoparticles were coupled with EGF. The obtained nanoparticles were characterized by ultraviolet-visible spectroscopy, transmission electron microscopy, X-ray photoelectron spectroscopy and zeta-potential before and after being coupled with the EGF. Gold nanoparticles with an average diameter of 8.09 nm were obtained. After coupled with EGF, the particle average diameter increased to 9.14 nm. X-ray photoelectron spectroscopy showed an electrostatic interaction between gold nanoparticles and EGF. Zeta potential corroborated these results. Thus, it was possible for the first time to identify the interactions between these two chemical species. Since gold nanoparticles may act as carriers of EGF, these results illustrate the great potential for the use of this bionanocomposite in neurodegenerative disease treatment.-
dc.descriptionUAEMEX-
dc.languageeng-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0-
dc.source1557-7910-
dc.subjectelectrostatic interactions-
dc.subjectcoupling gold nanoparticles-
dc.subjectepidermal growth factor-
dc.subjectneurodegenerative disease-
dc.subjectbionanocomposite-
dc.subjectinfo:eu-repo/classification/cti/7-
dc.titleStudy X-ray photoelectron spectroscopy determination of interactions between gold nanoparticles and epidermal growth factor for potential use in biomedicine-
dc.typearticle-
dc.audiencestudents-
dc.audienceresearchers-
item.grantfulltextnone-
item.fulltextNo Fulltext-
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