A novel and chemoselective process of N-alkylation of aromatic nitrogen compounds using quaternary ammonium salts as starting material

Please use this identifier to cite or link to this item: http://ri.uaemex.mx/handle20.500.11799/71098

Title:	A novel and chemoselective process of N-alkylation of aromatic nitrogen compounds using quaternary ammonium salts as starting material
Keywords:	N-alkylation;Quaternary Ammonium salts;Chemoselective;info:eu-repo/classification/cti/2
Publisher:	Hindawi
Description:	Artículo Internacional Open Acces The process of N-alkylation of several pyrroles, indoles, and derivative heterocycles is herein described, using quaternary ammonium salts as the source of an alkylating agent. These reactions were carried out on several heterocyclic rings with triethylbenzylammonium chloride or tetradecyltrimethyl ammonium bromide and an NaOH solution at 50%, leading to a chemoselective N-alkylated product and an average yield of 73%. This is an alternative process to the traditional benzylation and methylation of N-heterocycles with direct handling of alkyl halides. CONACYT, Secretaría de Investigación y Estudios Avanzados de la UAEM
URI:	http://ri.uaemex.mx/handle20.500.11799/71098
Other Identifiers:	http://hdl.handle.net/20.500.11799/71098
Rights:	info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-nd/4.0
Appears in Collections:	Producción

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