Please use this identifier to cite or link to this item: http://ri.uaemex.mx/handle20.500.11799/79865
Title: Atypical Klebsiella Species in a Third Level Hospital as Cause of Neonatal Infection
Authors: DAMIAN DAVID CIFUENTES CASTANEDA 
NINFA RAMIREZ DURAN 
ILIANA ESPINOZA RIVERA 
LUZ MARCELA CARO GONZALEZ 
MARTIN PABLO ANTONIO MORENO PEREZ 
HUGO MENDIETA ZERON 
Keywords: klebsiella;neonatal infection;atypical species;info:eu-repo/classification/cti/3
Publisher: Jundishapur J Microbiol.
Description: Aportamos una propuesta para analizar la agresividad de un patógeno en relación a la resistencia y sensibilidad antimicrobianas encontradas.
Background: The opportunistic pathogen Klebsiella pneumoniae is one of the main causes of pediatric bacterial blood stream infections (BSI), which is complicated with sepsis and high mortality. Objectives: To identify atypical Klebsiella species affecting a sample of infected neonates with low antimicrobial response. Methods: Multidrug resistant blood cultures for Klebsiella from a Neonatal Service, were submitted to molecular identification by sequencing analysis of 16S ribosomal RNA. Results: Themean age of the newborns was 14.7±5.6 days. A total of 6 out of 8 cases were sepsis, 1 case of pneumonia, and 1 a catheterrelated infection. The molecular identification showed 3 cases of K. pneumoniae subsp. ozaenae, 2 of K. pneumoniae and K. variicola, and 1 case of K. oxytoca. The highest antimicrobial resistance was against cephalosporins and Trimethoprim/sulfamethoxazole. Conclusions: Klebsiella pneumoniae subsp. ozaenae was responsible for multidrug resistant strains of Klebsiella even in 37.5% of cases. In our clinical setting, the use of Amikacin and carbapenems are still useful to treat neonatal infections by Klebsiella even against K. variicola, which is the most resistant
Ciprés Grupo Médico S.C. (CGM).
URI: http://ri.uaemex.mx/handle20.500.11799/79865
Other Identifiers: http://hdl.handle.net/20.500.11799/79865
Rights: info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0
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