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Please use this identifier to cite or link to this item: http://ri.uaemex.mx/handle20.500.11799/96909
DC FieldValueLanguage
dc.creatorANABELLA MARTINEZ DOMINGUEZ-
dc.creatorIRAZU CONTRERAS YANEZ-
dc.creatorJOSE ANTONIO ESTRADA GUADARRAMA-
dc.date2017-
dc.date.accessioned2022-04-21T06:00:46Z-
dc.date.available2022-04-21T06:00:46Z-
dc.identifierhttp://hdl.handle.net/20.500.11799/96909-
dc.identifier.urihttp://ri.uaemex.mx/handle20.500.11799/96909-
dc.descriptionOxidative stress (OS) is considered a risk factor for neurodegenerative disorders. Iron concentrations have been related to OS; however, the effect of iron deficiency (ID) on the induction of OS in the central nervous system (CNS) is unknown. A murine model of chronic diet-induced ID using 2 month-old male BALB/c mice (6 specimen), was used to determine its role in OS induction. Lipid peroxidation was determined by measuring thiobarbituric acid-reactive species (TBARS) in the CNS, using the spleen for comparison. A decrease of peroxidation products in the CNS of the ID group (ID CNS), compared to controls fed on a regular diet, was found. The spleen showed a significant increase of lipid peroxidation in the ID group. Our results suggest that chronic ID may have differential effects on OS in the CNS and peripheral tissues. A decreased amount of reactive oxygen species in the basal state may be related to alterations on normal CNS metabolism and functions under chronic ID.-
dc.formatapplication/application/pdf-
dc.languageeng-
dc.publisherUniversidad de Guanajuato-
dc.relationhttp://www.redalyc.org/revista.oa?id=416-
dc.rightsinfo:eu-repo/semantics/Acta Universitaria-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0-
dc.sourceActa Universitaria (México) Num.6 Vol.27-
dc.subjectMultidisciplinarias (Ciencias Sociales)-
dc.subjectOxidative stress-
dc.subjectlipid peroxidation-
dc.subjectiron deficiency-
dc.subjectcentral nervous system-
dc.subjectspleen-
dc.subjectMultidisciplinarias (Ciencias Sociales)-
dc.subjectOxidative stress-
dc.subjectlipid peroxidation-
dc.subjectiron deficiency-
dc.subjectcentral nervous system-
dc.subjectspleen-
dc.subjectinfo:eu-repo/classification/cti/5-
dc.titleOxidative damage in lipids in the central nervous system and spleen in iron-deficient mice-
dc.titleOxidative damage in lipids in the central nervous system and spleen in iron-deficient mice-
dc.typearticle-
dc.audiencestudents-
dc.audienceresearchers-
item.grantfulltextnone-
item.fulltextNo Fulltext-
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