Resumen:
An African hedgehog patient with generalised erythema and periauricular scaling was presented for consultation;
previously, it had been treated with ivermectin but no improvement was noted. Scrapes were performed from
the skin and the mite morphologically corresponded to Demodex spp. Demodicosis in African hedgehogs is fairly
rare; this is the reason why a molecular diagnosis was added to the microscopic diagnosis for this clinical case.
The common treatments for mites in hedgehogs are ivermectin, selamectin, flipronil, and amitraz; the
application of a single dose of afoxolaner/milbemycin oxime has not been previously reported. The molecular
and phylogenetic analysis showed that the species causing the demodicosis in the patient was Demodex canis. The
single oral dose of afoxolaner/milbemycin oxime reduced the number of mites to 0 in subsequent samples 7
days after the treatment and there were no lesions after 30 days.