Synthesis of Miconazole and Analogs Through a Carbenoid Intermediate

Canul, Adriana; Serrano, Juan Manuel; Cuevas, Erick; Cruz, Raymundo; Muchowski, Joseph M.

Synthesis of Miconazole and Analogs Through a Carbenoid Intermediate

Canul, Adriana; Serrano, Juan Manuel; Cuevas, Erick; Cruz, Raymundo; Muchowski, Joseph M.

URI: http://hdl.handle.net/20.500.11799/135684

Descripción:

"An alternative synthesis for the preparation of miconazole,enilconazole and econazole is described. The process involves theintermolecular insertion of a carbenoid species to imidazole from α-diazoketones with copper acetylacetonate as the key react

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