Mostrar el registro sencillo del objeto digital

dc.contributor.author RIVADENEIRA BARREIRO, PILAR ELIANA
dc.contributor.author Montes de Oca Jiménez, Roberto
dc.contributor.author Zambrano-Rodríguez, Pablo Cleomenes
dc.contributor.author Vázquez Chagoyán, Juan Carlos
dc.contributor.author Gutiérrez-Castillo, Adriana del Carmen
dc.contributor.author Pardo-Marin, Luis
dc.contributor.author Franco-Martínez, Lorena
dc.contributor.author Joaquín Cerón, José
dc.contributor.author Martínez-Subiela, Silvia
dc.date.accessioned 2024-02-21T18:15:50Z
dc.date.available 2024-02-21T18:15:50Z
dc.date.issued 2023-05-31
dc.identifier.issn 2414-6366
dc.identifier.uri http://hdl.handle.net/20.500.11799/140131
dc.description Artículo Científico es
dc.description.abstract Acute phase proteins have been used as tools for the diagnosis, monitoring, and prognosis of several diseases in domestic animals. However, the dynamics of these proteins in infection by Trypanosoma cruzi, the causative agent of Chagas disease in dogs, is still unknown. The aim of this study was to determine concentrations of acute phase proteins (C-reactive protein, haptoglobin, ferritin and paraoxonase-1) in dogs in a coastal town of Ecuador, with natural Trypanosoma cruzi infection with or without seroreactivity of Ehrlichia canis, Ehrlichia ewingii, Anaplasma phagocytophilum, Anaplasma platys, Borrelia burgdorferi and Dirofilaria immitis. For the detection of Trypanosoma cruzi serum antibodies, two different antigen-based enzyme-linked immunosorbent assay tests were implemented. For the detection of seroreactivity of Ehrlichia canis, Ehrlichia ewingii, Anaplasma phago cytophilum, Anaplasma platys, Borrelia burgdorferi and Dirofilaria immitis, an IDEXX SNAP® 4Dx® test was used. To determine the concentration of C-reactive protein and ferritin, an immunoturbidimetric assay was used; haptoglobin concentration was measured using a commercial colorimetric method validated in dogs; a spectrophotometric method was used to determine the serum concentration of paraoxonase-1. Results showed a reduction in the serum levels of paraoxonase-1 in Trypanosoma cruzi-seroreactive dogs, either with or without seroreactivity to other vector-borne diseases. A serum ferritin increment was observed in Trypanosoma cruzi-seroreactive dogs with seroreactivity to any other vector-borne diseases. Our findings suggest that paraoxonase-1 levels are reduced in Trypanosoma cruzi-seroreactive dogs without evident clinical signs of Chagas disease, despite their seroreactivity to the other vector-borne diseases studied. These findings could indicate an oxidative stress response in Trypanosoma cruzi-seroreactive dogs with no evident signs of inflammation es
dc.description.sponsorship UAEM es
dc.language.iso eng es
dc.publisher Tropical Medicine and Infectious Disease es
dc.rights openAccess es
dc.rights.uri http://creativecommons.org/licenses/by/4.0 es
dc.subject acute phase proteins es
dc.subject Chagas disease es
dc.subject dogs es
dc.subject ferritin es
dc.subject PON-1 es
dc.subject Trypanosoma cruzi es
dc.subject.classification CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA es
dc.title Acute Phase Proteins in Dogs with Natural Infection by Trypanosoma cruzi es
dc.type Artículo es
dc.provenance Científica es
dc.road Verde es
dc.organismo Medicina Veterinaria y Zootecnia es
dc.ambito Internacional es
dc.cve.CenCos 21401 es
dc.relation.vol 8
dc.relation.doi https://doi.org/10.3390/ tropicalmed8060299


Ficheros en el objeto digital

Este ítem aparece en la(s) siguiente(s) colección(ones)

Visualización del Documento

  • Título
  • Acute Phase Proteins in Dogs with Natural Infection by Trypanosoma cruzi
  • Autor
  • RIVADENEIRA BARREIRO, PILAR ELIANA
  • Montes de Oca Jiménez, Roberto
  • Zambrano-Rodríguez, Pablo Cleomenes
  • Vázquez Chagoyán, Juan Carlos
  • Gutiérrez-Castillo, Adriana del Carmen
  • Pardo-Marin, Luis
  • Franco-Martínez, Lorena
  • Joaquín Cerón, José
  • Martínez-Subiela, Silvia
  • Fecha de publicación
  • 2023-05-31
  • Editor
  • Tropical Medicine and Infectious Disease
  • Tipo de documento
  • Artículo
  • Palabras clave
  • acute phase proteins
  • Chagas disease
  • dogs
  • ferritin
  • PON-1
  • Trypanosoma cruzi
  • Los documentos depositados en el Repositorio Institucional de la Universidad Autónoma del Estado de México se encuentran a disposición en Acceso Abierto bajo la licencia Creative Commons: Atribución-NoComercial-SinDerivar 4.0 Internacional (CC BY-NC-ND 4.0)

Mostrar el registro sencillo del objeto digital

openAccess Excepto si se señala otra cosa, la licencia del ítem se describe cómo openAccess

Buscar en RI


Buscar en RI

Usuario

Estadísticas