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dc.contributor.author Mendieta Zerón, Hugo
dc.contributor.author PARADA FLORES, ALEJANDRO
dc.contributor.author AMAYA CHAVEZ, ARACELI
dc.contributor.author GARDUÑO ALANIS, ADRIANA
dc.contributor.author COLIN FERREYRA, MARIA DEL CARMEN
dc.contributor.author SANTILLAN BENITEZ, JONNATHAN GUADALUPE
dc.contributor.author Morales Castañeda, Violeta Saraí
dc.contributor.author DOMINGUEZ GARCIA, MA. VICTORIA
dc.creator Mendieta Zerón, Hugo; 45175
dc.creator PARADA FLORES, ALEJANDRO; 328190
dc.creator AMAYA CHAVEZ, ARACELI; 201356
dc.creator GARDUÑO ALANIS, ADRIANA; 225677
dc.creator COLIN FERREYRA, MARIA DEL CARMEN; 226658
dc.creator SANTILLAN BENITEZ, JONNATHAN GUADALUPE; 238940
dc.creator Morales Castañeda, Violeta Saraí;x1240941
dc.creator DOMINGUEZ GARCIA, MA. VICTORIA; 85954
dc.date.accessioned 2019-05-07T18:45:24Z
dc.date.available 2019-05-07T18:45:24Z
dc.date.issued 2013
dc.identifier.issn 1999-768X
dc.identifier.uri http://hdl.handle.net/20.500.11799/99927
dc.description.abstract Objective: Nuclear factor kappa B (NF-κB) pathway and oxidative stress participate in endothelial dysfunction, which is one of the causes of preeclampsia. Among the human antioxidant mechanisms there are the enzymes catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD). Our aim was to measure NF-κB, its inhibitor (IKK) and oxidative stress in placenta and umbilical cord of pregnant women submitted to a supervised nutritional program. Methods: Two groups were conformed: A) 14 pregnant women with individualized nutritional counseling and B) 12 pregnant women without nutritional guidance. NF-κB and IKK were assessed by real time PCR (RT-PCR). Enzymatic activity of CAT, GPx, lipoperoxidation (LPO) and SOD were also evaluated. Results: Pregnant women that followed-up a supervised nutritional program had lower level of systolic (p=0.03) and diastolic pressure (p=0.043) although they were heavier than a control group (p=0.048). Among all women, the Spearman correlation was positive between weight gain and placental NF-κB expression (1, p≤0.01). In placenta, women with nutritional advice had lower enzymatic activity of GPx (p≤0.038) and showed a tendency of IKK to be higher than in women without a nutritional supervised program. Conclusion: A supervised nutritional program in pregnancy offers a proven option to control weight gain, hypertension, NF-κB/IKK complex expression and oxidative stress reactions in placenta. es
dc.language.iso eng es
dc.publisher Oman Medical Specialty Board es
dc.rights openAccess
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject Pregnancy weight gain es
dc.subject Nutritional program es
dc.subject Placenta es
dc.subject NF-κB/IKK es
dc.subject Oxidative stress es
dc.subject.classification HUMANIDADES Y CIENCIAS DE LA CONDUCTA
dc.title Pregnancy weight gain limitation by a supervised nutritional program influences placental NF-κB/IKK complex expression and oxidative stress es
dc.type Artículo es
dc.provenance Científica es
dc.road Dorada es
dc.ambito Internacional es
dc.audience students es
dc.audience researchers es
dc.type.conacyt article
dc.identificator 4


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  • Título
  • Pregnancy weight gain limitation by a supervised nutritional program influences placental NF-κB/IKK complex expression and oxidative stress
  • Autor
  • Mendieta Zerón, Hugo
  • PARADA FLORES, ALEJANDRO
  • AMAYA CHAVEZ, ARACELI
  • GARDUÑO ALANIS, ADRIANA
  • COLIN FERREYRA, MARIA DEL CARMEN
  • SANTILLAN BENITEZ, JONNATHAN GUADALUPE
  • Morales Castañeda, Violeta Saraí
  • DOMINGUEZ GARCIA, MA. VICTORIA
  • Fecha de publicación
  • 2013
  • Editor
  • Oman Medical Specialty Board
  • Tipo de documento
  • Artículo
  • Palabras clave
  • Pregnancy weight gain
  • Nutritional program
  • Placenta
  • NF-κB/IKK
  • Oxidative stress
  • Los documentos depositados en el Repositorio Institucional de la Universidad Autónoma del Estado de México se encuentran a disposición en Acceso Abierto bajo la licencia Creative Commons: Atribución-NoComercial-SinDerivar 4.0 Internacional (CC BY-NC-ND 4.0)

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