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dc.contributor.author Griset MARTÍNEZ-LUNA
dc.contributor.author Julieta CASTILLO-CADENA
dc.contributor.author Jorge Humberto SERMENT-GUERRERO
dc.creator Griset MARTÍNEZ-LUNA
dc.creator Julieta CASTILLO-CADENA
dc.creator Jorge Humberto SERMENT-GUERRERO
dc.date 2015
dc.date.accessioned 2016-03-16T17:16:43Z
dc.date.available 2016-03-16T17:16:43Z
dc.identifier http://www.redalyc.org/articulo.oa?id=37036860003
dc.identifier.uri http://hdl.handle.net/20.500.11799/39050
dc.description The comet assay is a relatively inexpensive, fast, sensitive and reliable method to detect DNA breakage upon individual cells. The most widely used cell type in this technique is lymphocyte, because they are easy to obtain and handle, and because they are continually exposed to xenobiotics that enter into the body. However, is important to consider the possibility to use other cell types for very specific purposes. Sperm cells are of special interest because they could be used as a biomonitor to risk assessment in populations occupationally exposed to xenobiotics. Besides, the fact that there are not functional DNA repair mechanisms in these cells could increase the sensitivity of the system. We present here several modifications to the comet assay methodology to evaluate DNA breakage in sperm cells with reliable results.
dc.format application/pdf
dc.language eng
dc.publisher Universidad Nacional Autónoma de México
dc.relation http://www.redalyc.org/revista.oa?id=370
dc.rights openAcess
dc.rights Revista Internacional de Contaminación Ambiental
dc.source Revista Internacional de Contaminación Ambiental (México) Num.1 Vol.31
dc.subject Ciencias de la Tierra
dc.subject Genotoxicity
dc.subject DNA breakage
dc.subject sperm
dc.subject microelectrophoresis
dc.title MODIFIED PROCEDURE TO ASSESS DNA BREAKAGE IN SPERMATOZOA BY MEANS OF THE COMET ASSAY
dc.type Artículo
dc.provenance Científica
dc.road Dorada


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  • Título
  • MODIFIED PROCEDURE TO ASSESS DNA BREAKAGE IN SPERMATOZOA BY MEANS OF THE COMET ASSAY
  • Autor
  • Griset MARTÍNEZ-LUNA
  • Julieta CASTILLO-CADENA
  • Jorge Humberto SERMENT-GUERRERO
  • Editor
  • Universidad Nacional Autónoma de México
  • Tipo de documento
  • Artículo
  • Palabras clave
  • Ciencias de la Tierra
  • Genotoxicity
  • DNA breakage
  • sperm
  • microelectrophoresis
  • Los documentos depositados en el Repositorio Institucional de la Universidad Autónoma del Estado de México se encuentran a disposición en Acceso Abierto bajo la licencia Creative Commons: Atribución-NoComercial-SinDerivar 4.0 Internacional (CC BY-NC-ND 4.0)

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