Anaerobic fermentation of structural carbohydrates in the rumen of bovines produces waste products such as volatile fatty acids, fermentation heat, carbon dioxide and methane gas. Methane is a greenhouse gas having several times the global warming potential of CO 2 . The purpose of the present paper is to provide a realistic estimate of the national inventory of methane produced by the enteric fermentation of cattle, based on a simulation model and to provide estimates of CH 4 produced by cattle fed typical diets from the tropical and temperate climates of Mexico. Predicted total emission of methane produced by the 23.3 million heads of cattle in Mexico is approximately 2.02 Tg/yr. It was concluded that the modeling approach was suitable in producing a better estimate of the national methane inventory for cattle. It is flexible enough to incorporate more cattle groups or classification schemes, productivity levels and a variety feed ingredients for cattle. The model could also be used to evaluate different mitigation strategies and serve as a tool to design mitigation policies.