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dc.contributor Sánchez-Aparicio, Pedro
dc.contributor.advisor IBANCOVICHI CAMARILLO, JOSE ANTONIO; 251955
dc.contributor.author TAPIA GIL, ANDY
dc.creator TAPIA GIL, ANDY; 444065
dc.date.accessioned 2018-02-23T05:08:06Z
dc.date.available 2018-02-23T05:08:06Z
dc.date.issued 2017-12-05
dc.identifier.uri http://hdl.handle.net/20.500.11799/68870
dc.description.abstract Osteoarthritis (OA) is a degenerative disease and pain is the principal clinical sign. In advanced OA, there are cellular changes that perpetuate the pain response to mechanical, electrical and biochemical stimulus. Nonsteroidal anti-inflammatory drugs (NSAIDs) do not always provide sufficient pain relief in dogs with OA. Gabapentin is an anticonvulsive drug, which has shown effectively in relief several pain conditions. Fluoxetine is an antidepressant drug and seems to have efficacy in several chronic pain conditions. The objective was to measure the osteoarthritic pain, before and after of the medication with gabapentin and fluoxetine alone or in addition to Carprofen therapy and to compare groups to the final treatment. A total of 30 dogs were included and were randomly divided in 5 groups (n=6) and then were medicated for 8 weeks. Numerical Rating Scale and Helsinki Chronic Pain Index (HCPI) were used to assessment the osteoarthritic pain. For Numerical Rating Scale used for the Clinical Researcher observed significant difference in all treatment groups in week 4 and 8 except to group 5, which shown mild improvement in comparison to basal measurement. Owners used HCPI and observed physical activity increased significant in all groups since week 3 and group 3 since week 2 of treatment in comparison to basal measurement. In conclusion, Gabapentin alone, Gabapentin+Carprofen and Gabapentin+Fluoxetin relief OA pain and increased the physical activity significant in dogs with OA pain. es
dc.language.iso spa es
dc.publisher Universidad Autónoma del Estado de México es
dc.rights openAccess es
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject farmacologia es
dc.subject osteoartritis es
dc.subject gabapentina es
dc.subject fluoxetina es
dc.subject.classification CIENCIAS AGROPECUARIAS Y BIOTECNOLOGÍA
dc.title Comparación entre gabapentina y fluoexetina en el tratamiento del dolor provocado por osteoatritis es
dc.type Tesis de Maestría es
dc.provenance Científica es
dc.road Dorada es
dc.organismo Medicina Veterinaria y Zootecnia es
dc.ambito Internacional es
dc.cve.CenCos 21401 es
dc.cve.progEstudios 642- es
dc.modalidad Tesis es
dc.audience students
dc.audience researchers
dc.type.conacyt masterThesis
dc.identificator 6


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  • Título
  • Comparación entre gabapentina y fluoexetina en el tratamiento del dolor provocado por osteoatritis
  • Autor
  • TAPIA GIL, ANDY
  • Colaborador
  • Sánchez-Aparicio, Pedro
  • Fecha de publicación
  • 2017-12-05
  • Editor
  • Universidad Autónoma del Estado de México
  • Tipo de documento
  • Tesis de Maestría
  • Palabras clave
  • farmacologia
  • osteoartritis
  • gabapentina
  • fluoxetina
  • Los documentos depositados en el Repositorio Institucional de la Universidad Autónoma del Estado de México se encuentran a disposición en Acceso Abierto bajo la licencia Creative Commons: Atribución-NoComercial-SinDerivar 4.0 Internacional (CC BY-NC-ND 4.0)

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