Mostrar el registro sencillo del objeto digital

dc.contributor MORALES LUCKIE, RAUL ALBERTO
dc.contributor.author GONZALEZ PEDROZA, MARIA GUADALUPE
dc.date.accessioned 2020-02-11T20:03:04Z
dc.date.available 2020-02-11T20:03:04Z
dc.date.issued 2020-01-30
dc.identifier.uri http://hdl.handle.net/20.500.11799/105566
dc.description.abstract ABSTRACT Currently treatments for breast cancer are expensive and not very accessible, due to this, it requires the development of new routes of administration, treatments and novel materials, such as the one proposed. Carrying out the biosynthesis of silver nanoparticles (AgNPs) using extracts of a plant well known for its anticancer activity known as "Soursop" (Annona muricata); where the main active compounds of A. muricata (in leaves, stems and husk) are acetogenins and polyphenols, among others, which means that they can be used as reducing agents; It should be noted that anticancer activity is directly attributed to acetogenins. The biosynthesized AgNPs with leaf extract (AgNPs-EH) and with shell extract (AgNPs-EC) of A. muricata; were characterized by means of the UV-Vis technique, to observe the optical properties of the AgNPs, comparing the reaction times against the growth of the optical response known as Surface Plasmonic Resonance (RPS), as well as Transmission Electron Microscopy (TEM), to recognize the morphology and the average sizes of nanoparticle, with the help of the Scanning Electron Microscopy (SEM), a chemical mapping was achieved, to observe the distribution of the AgNPs in the medium, as well as with the help of the EDS technique (Energy-dispersive X-ray spectroscopy) the elemental chemical composition of the AgNPs was identified. In addition, by means of FT-IR it was possible to identify the vibrational mode of the functional groups present in the extracts. Achieving elucidate the cell viability of AgNPs in cell lines such as MCF-7, MDA-MB-468 and macrophages es
dc.language.iso spa es
dc.publisher Universidad Autónoma del Estado de México es
dc.rights openAccess es
dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0 es
dc.subject nanotechnology es
dc.subject silver nanoparticles es
dc.subject biosintesis es
dc.subject cancer es
dc.subject.classification BIOLOGÍA Y QUÍMICA es
dc.title BIOSÍNTESIS, CARACTERIZACIÓN Y EVALUACIÓN DE LA RESPUESTA ANTIPROLIFERATIVA DE NANOPARTÍCULAS DE PLATA, OBTENIDAS A BASE DE EXTRACTOS DE ANNONA MURICATA, SOBRE LÍNEAS CELULARES DE CÁNCER DE MAMA. es
dc.type Tesis de Doctorado es
dc.provenance Académica es
dc.road Verde es
dc.organismo Química es
dc.ambito Nacional es
dc.cve.CenCos 20403 es
dc.cve.progEstudios 763 es
dc.modalidad Tesis es


Ficheros en el objeto digital

Este ítem aparece en la(s) siguiente(s) colección(ones)

Visualización del Documento

  • Título
  • BIOSÍNTESIS, CARACTERIZACIÓN Y EVALUACIÓN DE LA RESPUESTA ANTIPROLIFERATIVA DE NANOPARTÍCULAS DE PLATA, OBTENIDAS A BASE DE EXTRACTOS DE ANNONA MURICATA, SOBRE LÍNEAS CELULARES DE CÁNCER DE MAMA.
  • Autor
  • GONZALEZ PEDROZA, MARIA GUADALUPE
  • Colaborador
  • MORALES LUCKIE, RAUL ALBERTO
  • Fecha de publicación
  • 2020-01-30
  • Editor
  • Universidad Autónoma del Estado de México
  • Tipo de documento
  • Tesis de Doctorado
  • Palabras clave
  • nanotechnology
  • silver nanoparticles
  • biosintesis
  • cancer
  • Los documentos depositados en el Repositorio Institucional de la Universidad Autónoma del Estado de México se encuentran a disposición en Acceso Abierto bajo la licencia Creative Commons: Atribución-NoComercial-SinDerivar 4.0 Internacional (CC BY-NC-ND 4.0)

Mostrar el registro sencillo del objeto digital

openAccess Excepto si se señala otra cosa, la licencia del ítem se describe cómo openAccess

Buscar en RI


Buscar en RI

Usuario

Estadísticas