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dc.contributor.author Anayo Orji, Frank
dc.contributor.author Chinyere Ugbogu, Ositadinma
dc.contributor.author Ugbogu, Eziuche Amadike
dc.contributor.author Barbabosa-Pliego, Alberto
dc.contributor.author Monroy, Jose Cedillo
dc.contributor.author Elghandour, Mona M.M.Y.
dc.contributor.author Salem, Abdelfattah Z.M.
dc.date.accessioned 2019-02-21T17:16:05Z
dc.date.available 2019-02-21T17:16:05Z
dc.date.issued 2018-05-05
dc.identifier.issn 0882-4010
dc.identifier.uri http://hdl.handle.net/20.500.11799/99053
dc.description.abstract Over 250 species of resident flora in the class of bacteria are known to be associated with humans. These conventional flora compositions is often determined by factors which may not be limited to genetics, age, sex, stress and nutrition of humans. Man is constantly in contact with bacteria through media such as air, water, soil and food. This paper reviews the concept of bacterial pathogenesis from the sequential point of colonization to tissue injury. The paper in addition to examination of the factors which enhance virulence in bacterial pathogens also x-rayed the concept of pathogenicity islands and the next generation approaches or rather current trends/methods used in the bacterial pathogenicity investigations. In terms of pathogenicity which of course is the capacity to cause disease in animals, requires that the attacking bacterial strain is virulent, and has ability to bypass the host immune defensive mechanisms. In order to achieve or exhibit pathogenicity, the virulence factors required by microorganisms include capsule, pigments, enzymes, iron acquisition through siderophores. Bacterial Pathogenicity Islands as a distinct concept in bacterial pathogenesis are just loci on the chromosome or extra chromosomal units which are acquired by horizontal gene transfer within pathogens in a microbial community or biofilm. In the area of laboratory investigations, bacterial pathogenesis was initially carried out using culture dependent approaches, which can only detect about 1% of human and veterinary-important pathogens. However, in the recent paradigms shift, the use of proteomics, metagenomics, phylogenetic tree analyses, spooligotyping, and finger printing etc. have made it possible that 100% of the bacterial pathogens in nature can be extensively studied. es
dc.language.iso eng es
dc.publisher Microbial Pathogenesis es
dc.relation.ispartofseries 121;1
dc.rights embargoedAccess es
dc.rights https://creativecommons.org/licenses/by-sa/4.0/ es
dc.rights embargoedAccess es
dc.rights https://creativecommons.org/licenses/by-sa/4.0/ es
dc.subject pathogenic bacteria es
dc.subject Colonization es
dc.subject Tissue injury es
dc.subject Diseases es
dc.title The conventional pathogenic flora compositions: An overview of the trends used for bacterial pathogenicity identifications es
dc.type Artículo es
dc.provenance Científica es
dc.road Dorada es
dc.organismo Medicina Veterinaria y Zootecnia es
dc.ambito Internacional es
dc.cve.CenCos 21401 es


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  • Título
  • The conventional pathogenic flora compositions: An overview of the trends used for bacterial pathogenicity identifications
  • Autor
  • Anayo Orji, Frank
  • Chinyere Ugbogu, Ositadinma
  • Ugbogu, Eziuche Amadike
  • Barbabosa-Pliego, Alberto
  • Monroy, Jose Cedillo
  • Elghandour, Mona M.M.Y.
  • Salem, Abdelfattah Z.M.
  • Fecha de publicación
  • 2018-05-05
  • Editor
  • Microbial Pathogenesis
  • Tipo de documento
  • Artículo
  • Palabras clave
  • pathogenic bacteria
  • Colonization
  • Tissue injury
  • Diseases
  • Los documentos depositados en el Repositorio Institucional de la Universidad Autónoma del Estado de México se encuentran a disposición en Acceso Abierto bajo la licencia Creative Commons: Atribución-NoComercial-SinDerivar 4.0 Internacional (CC BY-NC-ND 4.0)

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